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静脉窦孤立加异常回流静脉截断术治疗静脉窦型硬脑膜动静脉瘘
  • ISSN号:0376-2491
  • 期刊名称:中华医学杂志
  • 时间:2013.3.5
  • 页码:668-671
  • 分类:R743.4[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]复旦大学附属华山医院神经外科,上海200040
  • 相关基金:国家自然科学基金青年科学基金(81100860)
  • 相关项目:2-甲氧雌二醇对硬脑膜动静脉瘘血管生成/抑制因子平衡漂移的调控作用及其机制
中文摘要:

目的 分析静脉窦孤立术加异常回流静脉截断治疗大静脉窦旁硬脑膜动静脉瘘的长期效果.方法 连续性治疗15例患者中,瘘口位于上矢状窦7例,内侧横窦及窦汇附近3例,外侧横窦及乙状窦5例.症状包括颅高压,出血等.1例伽玛刀治疗无效后手术,1例栓塞后手术.患者采用静脉窦孤立加异常回流静脉截断术治疗,12例静脉窦保留,3例静脉窦完全闭塞段切除.结果 无手术死亡.出院时症状好转12例,不变2例,加重1例;随访11例,平均随访6年.KPS评分90分以上者8例,80分1例,60分和40分各1例;术后数字减影血管造影复查9例、CT血管造影1例,7例治愈,3例好转.结论 静脉窦孤立术可阻断绝大多数通向瘘口的供血动脉,达到治愈或长期缓解.

英文摘要:

Objective To retrospectively explore the long-term efficacies of sinus skeletonization plus abnormal venous reflux interruption in the treatment of dural arteriovenous fistula interfering major dural sinus.Methods Among 15 consecutively treated patients,the lesions were located in superior sagittal sinus (n =7),medial segment of transverse sinus (n =3) and lateral transverse and sigmoid sinus (n =5).And 40% of them clinically presented with intracranial hypertension and 13.3% with hemorrhage.Preoperatively,Gamma knife therapy and transarterial occlusion were used in 1 case each.All underwent sinus skeletonization plus abnormal venous reflux interruption if any.Interfered sinus was preserved in 12 cases.In another 3 cases,completely occluded segment of sinus was resected after skeletonization.Results Surgical mortality was none.At discharge,the symptoms were relieved or disappeared in 12 cases.Followup study was available in 11 cases over a mean period of 6 years.A Karnofsky performance status (KPS) score of 90 or more was achieved in 8 cases and a KPS score of 80,60 or 40 was found in 1 case each.Digital subtract angiography was performed in 9 cases and computed tomographic angiography in 1 case after operation.Cure was achieved in 7 cases and 3 cases had minimal residue without recurrence.Conclusion Sinus skeletonization may stably block most blood supply to fistula so as to offer cure or long-term control of dural arteriovenous fistula.

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期刊信息
  • 《中华医学杂志》
  • 北大核心期刊(2011版)
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京市东四西大街42号
  • 邮编:100710
  • 邮箱:nmjc@cma.org.cn
  • 电话:010-85158355 85158180
  • 国际标准刊号:ISSN:0376-2491
  • 国内统一刊号:ISSN:11-2137/R
  • 邮发代号:2-588
  • 获奖情况:
  • 1992年与1996年连续两次在中宣部、国家科委、新闻...,1999年、2003年分别荣获首届国家期刊奖和第二届国...,中国期刊方阵“双高”期刊
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  • 美国化学文摘(网络版),荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:101941