中文摘要：

建立通过高速逆流色谱从北五味子中快速分离科罗索酸的方法。将北五味子的乙醇提取物经AB-8大孔树脂初步纯化后直接采用高速逆流色谱进行分离，并通过高效液相色谱法考察了粗提物在不同溶剂体系中的分配情况。结果表明，最佳溶剂体系为正己烷-乙酸乙酯-甲醇-水（6：5：5：4，V／V）从150mg粗提物中一次性分离制备得到6．3mg纯度为97．6％的科罗索酸。该方法分离效率较高，对科罗索酸在食品医药领域的应用具有重要意义。

英文摘要：

An effective and rapid method for the separation of corosolic acid from Schisandra chinensis （S. chinensis） （Turcz.） Baill by high-speed counter-current chromatography （HSCCC） was established. The alcohol extract of S. chinensis （Turcz.） Baill was initially separated using AB-8 macroporous resins and further purified by HSCCC. A high performance liquid chromatography （HPLC） method was used to determine the partitioning coefficient of crude extract in different solvent systems. The results showed a solvent system consisting of n-hexane, ethyl acetate, methanol and water （6：5：5：4, V/V） was the best one for the HSCCC separation. A total of 6.3 mg of corosolic acid with a purity as high as 97.6% was obtained in one step separation from 150 mg of crude extract. The method is of high separation efficiency, and has a great importance for applications of corosolic acid in the food and medical fields.