中文摘要：

建立了醋酸甲酯加氢制乙醇的工艺流程,采用化工流程模拟与分析软件Aspen Plus进行了系统的模拟研究。通过对工艺条件的分析,获得了过程较优的工艺参数。提出使用变压精馏的方法分离醋酸甲酯-甲醇共沸物,低压塔采用常压操作,较优的高压塔操作压力为1.1MPa。同时针对多组分分离精馏序列的问题,模拟对比了逆序精馏和顺序精馏2种工艺,年度总费用（Total annualized cost,TAC）分析表明,首先分离出乙醇的逆序精馏工艺更经济合理。

英文摘要：

The process of hydrogenation of methyl acetate to ethanol was developed and simulated by the chemical process and analysis software of Aspen Plus. The number of theoretical stages, the reflux ratio, the feeding position of each column and the feeding way of methanol refined column were obtained by the analysis tool of the software. A method with different pressure distillation system to separate methyl acetate-methanol azeotrope was put forward, and the operating pressure of high pressure column was determined to be 1. 1MPa, while the low pressure column was at atmospheric pressure. Meanwhile,two different chemical processes,distillation flowsheet of inverted sequence and sequence, were simulated and optimized based on distillation sequences on multi components, and analyzed by total annualized cost （TAC） analysis. The results demonstrated that the inverted sequence, in which ethanol was first separated, was more reasonable and economical.