中文摘要：

目的分析超声引导下经皮微波消融治疗乳腺良性结节的疗效。方法回顾性研究2013年11月-2016年8月我科收治的164例接受超声引导下经皮微波消融治疗乳腺良性结节患者的临床资料,分析所有患者的肿瘤灭活情况、体积缩小程度、消融时间、术后即刻疼痛症状评分、美观满意程度和并发症。结果 164例患者经穿刺活检证实良性结节261个,其中116个病灶邻近皮肤、胸壁和乳晕。肿瘤直径为1.5±0.7（0.3~4.4）cm。核磁共振和超声评估的完全消融率分别为99.2%和100%。平均消融时间为2.9（0.5~18.3）min。平均随访14个月,肿块可触及率由微波消融前的90.2%降至随访末期的43.9%。消融后12个月所有结节的平均体积缩小率为80%±20%,其中直径≤1.0 cm、1.1~2.0 cm及〉2.0 cm的结节体积缩小率分别为80%±33%、76%±22%、53%±34%。术后即刻疼痛症状评分为0.57±0.50,消融后无其他并发症及不良反应发生。美观性方面,100%患者获得良好满意度。结论超声引导经皮微波消融治疗乳腺良性结节是微创、安全、有效的,同时取得了较好的美观满意效果。

英文摘要：

Objective To analyze the therapeutic effect of ultrasound guided percutaneous microwave ablation（MWA） for treatment of breast benign lesions（BBLs）. Methods Clinical data about 164 patients with 261 breast benign lesions admitted to our department from November 2013 to August 2016 were analyzed. One hundred and sixteen lesions adjacent to the skin, pectoralis and areola were included. All patients underwent ultrasound guided percutaneous microwave ablation and all the lesions were biopsy-proved benign. The complete ablation of the tumors, volume reduction rate, operating time, immediate post-operative pain scoring and aesthetic satisfaction were evaluated. Results The mean diameter of tumors was（1.5±0.7） cm（range 0.3-4.4 cm）. MWA was successfully performed in all cases with complete ablation rate of 99.2% assessed by magnetic resonance imaging and 100% by ultrasound. The mean ablation time was 2.9 min（range 0.5-18.3 min）. The median follow-up period was 14 months, and the BBLs were palpable in 43.9% of the cases, while they were palpable in 90.2% of the cases before MWA. The mean volume reduction rate was 80%±20% for total lesions at 12 months after ablation and it was 80%±33%, 76%±22%, 53%±34% for lesions≤1.0 cm, 1.1-2.0 cm and2.0 cm, respectively. The immediate post-operative pain score was 0.57±0.50. Cosmesis assessment was reported as good or excellent in all patients. No complication or side effect was found in all cases. Conclusion Ultrasound guided percutaneous microwave ablation for breast benign nodules is a minimally invasive, safe and effective treatment with meaningful reduction in volume and satisfying in appearence.