中文摘要：

对链霉菌G-HD-4发酵液采用酸沉淀、碱性溶液提取、酸水解，以及多种有机溶剂抽提等工艺手段分离、纯化出黑色素，研究其理化性质．结果表明，该黑色素的最大吸收峰为246nm，与标准黑色素最大吸收峰相一致．在400nm波长下，其光密度值（D）随黑色素质量浓度的增加而增大；容易被强氧化剂所氧化，而紫外、光照、温度、有机溶剂、还原剂、各种盐，以及金属离子对黑色素的影响较小，氨基酸、淀粉等添加物对黑色素稳定性没有影响，说明该黑色素稳定性良好．

英文摘要：

The melanin derived from ferment broth of Streptomyces G-HD-4 was isolated and purified by acid deposition, alkaline extraction, acid hydrobysis and multiplicate organic solvents extraction, and their physical and chemical properties were studied. The result shows that the maximum absorption peak of the melanin was 246 nm which agree with the typical melanin. The absorbance of the melanin increase with an increase of melanin＇s concentration at 400 nm. The melanin could be bleached by strong oxidants, but it had tess sensitivity to ultraviolet light or room light, temperature, organic solvents, reducing agents, salts and metal-ions for the melanin. Different of additions such as amino acid, starch et al, had no effect on the stability of melanin. Physical and chemical properties of the melanin revealed that the melanin from Streptomyces G-HD-4 had a favorable stability.