顺-1-呋喃乙酰基-2-对位取代苯基-6,6-二甲基-5,7-二氧-螺-[2,5]-4,8-辛二酮和顺-1-噻吩乙酰基-2-对位取代苯基-6,6-二甲基-5,7-二氧-螺-[2,5]-4,8-辛二酮与甲醇于封管中80℃反应72h得到β-呋喃甲酰基-γ-甲氧基-γ-对取代苯基-丁酸甲酯及β-噻吩甲酰基-γ-甲氧基-γ-对取代苯基-丁酸甲酯。其结构经^1H NMR。^13C NMR,IR,MS及APT。讨论了反应机理。
Methyl β-furoyl-γ-p-substituted phenyibutyrates or methyl β-thienoyl-γ-p-substituted phenylbutyrates was synthesized by the reaction of 1,2,3-trisubstituted electron-deficient cyclopropane derivatives cis-1-furoyl-2-p-substituted phenyl-6,6-dimethyl-5,7-dioxa-spiro- [ 2,5 ] -4,8-octadiones or cis-1 -thienoyl-2-p-substituted phenyl-6,6-dimethyl-5,7 -dioxa-spiro- [ 2,5 ] -4,8 -octadiones with methanol at 80 ℃ for 72 h in a sealed tube. The structures were confirmed by ^1 H NMR, ^13 C NMR, IR, MS and APT. The reaction mechanism for the formation of the products was also proposed.