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中文摘要：
术后慢性疼痛具有发病率高、持续时间长、危险因素多、发病机制复杂等特点,在开胸术后尤为常见,严重影响患者的生活质量。手术所致神经病理性损伤是术后慢性疼痛发生的重要原因。与此同时,手术损伤所致神经系统的过度炎症反应和多种炎症细胞因子释放亦加快术后慢性疼痛的形成。本文主要综述术后神经系统炎症反应和炎症细胞因子在术后慢性疼痛发生发展中的作用。
英文摘要：
Chronic postsurgical pain（ CPSP） is characterized by high incidence,prolonged duration,multiple risk factors,and complicated pathogenesis. It seriously impairs patients＇ quality of life,especially after thoracotomy. Perioperative nerve injury is a major cause of CPSP. Meanwhile,the excessive neuroinflammation and inflammatory cytokines caused by surgery also accelerate the formation of CPSP. This review aims to provide an overview of the recent advances in the roles of inflammatory reaction and cytokines in the development of CPSP.
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Expressions of Neuropathic Pain-related Proteins in the Spinal Cord Dorsal Horn in Rats with Bilater
MiR-203 Involves in Neuropathic Pain Development and Represses Rap1a Expression in Nerve Growth Fact
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