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Polyelectrolyte multilayer patterns created by capillary force and their impact on cell migration

ISSN号：1001-604X
期刊名称：Chinese Journal of Chemistry
时间：2013.12.12
页码：0-0
分类：TS952.83[轻工技术与工程] TP332[自动化与计算机技术—计算机系统结构;自动化与计算机技术—计算机科学与技术]
作者机构：MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhengjiang 310027, China, Email: Zhengwei Mao (zwmao@zju.edu.cn)[*]MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhengjiang 310027, China, Fax: 0086-571-87951108
相关基金：This study is financially supported by the National Natural Science Foundation of China (Nos.20934003and 51003094),and the National Basic Research Program of China (No.2011CB606203).Z.W.Mao thanks Young Teacher Programs Foundation of Ministry of Education of China (No.20100101120034),'Qianjiang'outstanding researcher funding of Zhejiang Province (No.J20110541) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry.
相关项目：调控细胞迁移与分化的梯度医用高分子材料研究

作者： Lulu Han, Jindan Wu, Tanchen Ren, Zhengwei Mao, Y|

关键词： CAPILLARY, force, LITHOGRAPHY, POLYELECTROLYTE, multilayer, cell, migration, RIDGE, height, salt, ETCHING, capillary force lithography, polyelectrolyte multilayer, cell migration, ridge height, salt etching

中文摘要：

房间移植在许多生理、病理学的进程起一个关键作用。在这学习平版印刷术 poly 习惯于对待的毛状的力量的一个方法(钠 4-styrenesulfonate )( PSS )有在由 NaCl 答案蚀刻前后的一枚 PDMS 邮票的 /poly ( diallyldimethylammonium )氯化物( PDADMAC ) multilayers ，有象两倍细线那样的各种各样的特征的让步的物理模式，加倍脱衣，塑造新月的山脉，和高山脉。山脉高度在 25 和 1100 nm 的范围是可控制的。光滑的肌肉房间(SMC ) 的移植被双线模式以一种山脉高度依赖者方式制止。由对比， SMC 的活动性被两个控制 multilayers 和模式的水和比率展示。

英文摘要：

Cell migration plays a crucial role in a variety of physiological and pathological processes.In this study a method of capillary force lithography was used to treat poly(sodium 4-styrenesulfonate) (PSS)/poly(diallyldimethylammonium) chloride (PDADMAC) multilayers with a PDMS stamp before or after etching by NaC1 solution,yielding physical patterns with various features such as double thin lines,double strips,meniscus-shaped ridges,and high ridges.The ridge height is controllable in the range of 25 and 1100 nm.Migration of smooth muscle cells (SMCs) was restrained by the double-line patterns in a ridge height-dependent manner.By contrast,the mobility of SMCs was controlled by both the hydration ratio of the multilayers and the pattern features.

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