单细胞网络谱分析( single cell network profiling, SCNP)无需分离细胞的情况下,可检测分析复杂组织中不同类型细胞信号通路蛋白的表达水平及蛋白间网络调节关系,其在细胞水平上,可阐明疾病发生机制、将疾病重新精确分类、提高疾病诊断准确性,并为组合用药及药物筛选提供重要且丰富的信息,促进个体化治疗的实现。
SCNP( single cell network profiling) assay can depict the characters of signal pathway network without isolating the dif-ferent cells in advance in complex tissues. It will promote the disease mechanism elucidating, disease classification, diagnosis, and therapeutic regimen at cell level. Drug screening and ration-al personalized treatment will also be improved.