中文摘要：

成纤维细胞生长因子受体3（FGFR3）在调节细胞的增殖、分化及血管形成中发挥重要作用。近年来,研究发现FGFR3在乳腺癌发生发展和内分泌治疗耐药性乳腺癌中发挥一定的作用,并且与乳腺癌患者的预后密切相关。

英文摘要：

Fibroblast growth factor receptor 3（FGFR3） plays important roles in cell proliferation, differentiation, and angiogenesis. Recent studies have demonstrated that FGFR3 is associated with progression of breast cancer and has effects in endocrine therapy resistance breast cancer. It has also been showed that FGFR3 is correlated with breast cancer prognosis.