中文摘要：

miRNA相关的单核苷酸多态性可以影响肿瘤的发展、治疗效果和临床结局。因此,作为生物标志物,miRNA相关的单核苷酸多态性可以用来评估个体对肿瘤的易感性,预测患者的临床结局,进而,为肿瘤的临床治疗提供新的策略。

英文摘要：

microRNA-related single nucleotide polymorphisms （miRNA-SNPs） may exert influences on tumor de- velopment, treatment efficacy and clinical outcomes. Thus, as biomarkers, miRNA-SNPs can be applied to evalu- ate the tumor susceptibility for individuals and play an predictive role in patients＇ clinical outcomes.