中文摘要：

以黄曲霉毒素B1污染玉米（Aflatoxin B1—contaminatedcorn，ACC）为原料，评估经90rag／I，臭氧处理40min的ACC（83．0gg／kg）在小鼠体内的毒性。结果表明，与基础饲料相比，ACC饲喂小鼠的平均体重显著降低（P〈0．05），肝脏与肾脏体重比显著增加（P〈0．05），血清中谷丙转氨酶、谷草转氨酶和碱性磷酸酶活性显著升高（P〈0．05），总蛋白、白蛋白和球蛋白含量显著降低（P〈O．05）。而ACC经臭氧处理后饲喂小鼠，小鼠体重、饲料消耗量、肝脏与肾脏体重比均无显著差异，血清中谷丙转氨酶活性、总蛋白、白蛋白和球蛋白含量也无显著差异（P〉0．05）；而谷草转氨酶和碱性磷酸酶活性显著升高（P〈0．05）。ACC可导致小鼠多项生理、生化指标发生显著变化，而ACC经臭氧处理后能显著改善其变化。

英文摘要：

Aflatoxin Bl contaminated corn （ACC） （83.0μg/kg） was treated for 40 min at 90 mg/L ozone. And mice were used to assess the vivo toxicity of ozone treated ACC. Results indicated that compared with basal feedstuff, the mean weight of mice fed with ACC significantly decreased （P〈0.05 ）. Whereas, the liver and kidney/body weight ratio increased significantly （P〈0.05 ）. Alanine t rans aminase （ ALT）, aspartate aminotransferase （ AST）, and alkaline phosphatase （ALP） in serum increased significantly （P〈0.05）. The total protein （TP）, albumin （ALB）, and globulin （GLB） content significantly decreased （P〈0.05）. When mice were fed with the o zone-treated ACC, no significant differences were observed in the mice mean weight, as well as the liver and kidney/body weight ratio. Additionally, no significant differences occurred in the major serum indexes ALT, TP, ALB, and GLB （P〉0.05）. Meanwhile, AST and AI,P increased significandy （P〈0.05）, The study indicated that ACC can lead to significant changes in various physiological characteristics and biochemical indexes in liver and kidney tissues, while the ozonetreated ACC could significantly improve these changes.