中文摘要：

丝状真菌由于其胞外蛋白分泌的高效性，成为生产酶制剂的高效细胞工厂．近年来针对真核生物胞外蛋白分泌途径的研究发现，丝状真菌蛋白的分泌途径相比其他真核生物具有高效分泌的特性．为了研究丝状真菌高效分泌的机制，本文总结了近年来丝状真菌分泌途径的最新研究进展，并且选取了分泌途径中关键环节的数种蛋白进行分析，通过与其他真核生物相关蛋白进行结构与序列比对，推测了丝状真菌胞外蛋白高效分泌的可能机制．

英文摘要：

Filamentous fungi are efficient cell factories in producing industrial enzyme products as the efficiency in extracellular proteins secretion. Most researches on extracellular proteins secretion in new century found that the protein secretion pathway of filamentous fungi had an efficient secretion mechanism compared with other eukaryotes＇. In order to explore the efficient mechanism, this paper summarized the latest research progresses of secretory pathway in filamentous fungi. The key proteins in the secretory pathway were selected to perform sequence alignment and structure alignment. And the possible efficient secretion mechanism was put forward.