中文摘要：

对采自海南文昌红树林根际土壤样品中分离到的真菌Penicillium sp.MA-37的次生代谢产物的化学成分进行了研究。利用硅胶柱层析、葡聚糖凝胶Sephadex LH-20柱层析、制备薄层层析以及重结晶等分离方法并通过现代波谱技术共分离、鉴定了8个天然产物,分别为：氮-（2-甲氧基-4-羟基苯）-丙酰胺酸（1）,氮-（2,4-二甲氧基苯）-丙酰胺酸（2）,氮-（2,4-二甲氧基苯）-丙酰胺酸甲酯（3）,（22E,24R）-麦角甾-5,7,22-三烯-3β-醇（4）,（22E,24R）-麦角甾-4,6,8（14）,22-四烯-3-酮（5）,（22E,24R）-5α,8α-环二氧麦角甾-6,22-双烯-3β-醇（6）,asperamide B（7）,cis-4-hydroxy-6-deoxyscytalone（8）;其中化合物1为新化合物,化合物2和3为新天然产物。

英文摘要：

From the fermentation culture of strain Penicillium sp.MA-37 derived from mangrove rhizosphere,eight compounds were isolated by separation techniques including column chromatography with silica gel and Sephadex LH-20,preparative TLC and re-crystallization.Structures of all purified compounds were elucidated by analysis of their spectroscopic data to be N-（2-methoxy-4-hydroxyphenyl）-malonamic acid（1）,N-（2,4-dimethoxyphenyl）malonamic acid（2）,N-（2,4-dimethoxyphenyl）-malonamic acid methyl ester（3）,（22E,24R）-ergosta-5,7,22-trien3β-ol（4）,（22E,24R）-Ergosta-4,6,8（14）,22-tetraen-3-one（5）,（22E,24R）-5α,8α-epidioxyergosta-6,22-dien-3β-ol（6）,asperamide B（7）,cis-4-hydroxy-6-deoxyscytalone（8）.Compound 1 was a new compound,while compounds 2 and 3 were reported as natural products for the first time.