中文摘要：

以芴为原料，通过卤代、Sonogashira偶联、钯催化交叉偶联反应等合成了目标化合物7-乙炔基-2-芴基膦酸二乙酯。采用核磁共振谱（1H、13C、31P NMR）、傅里叶变换红外光谱（FT-IR）、液质联用飞行时间质谱（LC-MS TOF）等对目标化合物进行结构表征，表征数据与化合物结构相符。本文采用一步法直接合成膦酸酯，与传统的两步法相比，操作步骤更加简化，反应条件温和，避免使用五氯化磷、二氧化硫等毒性原料，钯催化交叉偶联反应产率高达91％。

英文摘要：

T his paper described the synthesis of the title compound diethyl 7-ethynyl-2-fluorenylphosphonate using fluorene as starting material by halogenation , Sonogashira coupling , palladium-catalyzed cross-coupling reactions .The structure of the title compound was characterized and confirmed by NMR （1H ,13C and 31P） ,FT-IR ,LC-MS TOF spectra .Compared with traditional two steps method , this method has advantages of one-step synthesis of aryl phosphonate , simplification of operation process , avoiding using poisonous PCl5 and SO2 , moderate reaction condition ,and the yield of Pd-catalyzed cross-coupling reaction as high as 91% .