中文摘要：

为阐明人工心脏植入方式对主动脉内微栓运动的影响规律，首先，根据临床心哀患者的CT数据重建个性化真实主动脉模型，在此基础上耦合人工心脏串联植入与旁路植入模型，其中人工心脏泵植入主动脉内与心脏形成串联模式，旁路植入模式是人工心脏泵植入到心尖与升主动脉之间；其次，采用离散相理论和有限元方法对该模型进行血流动力学研究，获得不同人工心脏植入方式下主动脉内血流动力学的变化以及微栓分布数据；最后，对微栓分布数据进行统计学分析，获得人工心脏植入方式对主动脉内微栓运动的影响规律．串联植入方式下，进入降主动脉的概率是69．43％，微栓运动轨迹较规律；旁路植入方式下，进入降主动脉的概率为86．16％，微栓运动轨迹较紊乱．人工心脏的不同辅助方式改变了主动脉内血流动力学环境，从而可能影响微栓在主动脉内的运动规律．

英文摘要：

This paper aims to clarify the effects of different implanted types of artificial heart on microemboli movement in the aorta. Firstly, a patient-specific model of aorta derived from CT data of a clinical heart failure patient was reconstructed, and the two implanted types, including the aorta implantation ( aortic root to aortic arch ) and bypass implantation ( apex to ascending aorta ) , were established based on this model. Secondly, the discrete phase theory and finite element method was combined to obtain the distribution of microemboli in the aorta under both implanted types. Finally, the relationship between the movements of microemboli in the aorta and the implanted types was clarified by statistical analysis. The results showed that 69. 43% and 86. 16% of microemboli reached the descending aorta under aorta implantation and bypass implantation, the particle trajectory was regularly for aorta implantation, but the particle trajectory disorganized. In conclusion, the different implant types of artificial heart may change the hemodynamics environment, and it maybe influence the movement of microemboli in the aorta.