中文摘要：

有狭窄的尺寸分布的 Superparamagnetic 氧化铁 nanoparticles 被一个灵巧的一个壶成功地在大规模准备合成方法面对吸水的聚合物，例如聚乙烯乙二醇二酸(HOOC-PEG-COOH ) 并且 poly (丙烯酸的酸)( 泛美航空公司) 。同样准备的产品被粉末 X 光检查衍射(XRD ) 详细调查， thermogravimetric 分析(TGA ) ，传播电子显微镜学(TEM ) ，高分辨率的传播电子显微镜学(HRTEM ) ，散布，并且颤动的动态光(DLS ) 样品磁强计(VSM ) 。在聚合物和氧化铁 nanoparticles 之间的相互作用用 Fourier 被调查转变红外线的 spectrometry (英尺红外) 。结果证明聚合物能被分别地衔接协作和 monodentate 时尚依附到氧化铁 nanoparticle 的表面上。相互作用显著地影响氧化铁 nanoparticle 性质，例如 XRD 衍射紧张，水动力学直径，等电位的点，和浸透磁化。而且，结果在显示的 vitro 实验，那铁 oxide-PEG-COOH nanoparticle 比氧化铁更细胞毒素 -- 泛美航空公司 nanoparticle 由于不同协调模式。

英文摘要：

Superparamagnetic iron oxide nanoparticles with narrow size distributions were successfully prepared in large scale by a facile one-pot synthetic method in the presence of hydrophilic polymers, such as polyethylene glycol dia-cid （HOOC-PEG-COOH） and poly（acrylic acid） （PAA）. The as-prepared products were investigated in detail by powder X-ray diffraction （XRD）, thermogravimetric analyses （TGA）, transmission electron microscopy （TEM）, high-resolution transmission electron microscopy （HRTEM）, dynamic light scattering （DLS）, and vibrating sample magnetometer （VSM）. The interaction between polymers and iron oxide nanoparticles was investigated using Fou-rier transform infrared spectrometry （FT-IR）. The results show that polymers can be attached onto the surface of iron oxide nanoparticle by bridging coordination and monodentate fashion, respectively. The interaction affects iron oxide nanoparticle properties significantly, such as XRD diffraction intensity, hydrodynamic diameter, isoelectric point, and saturation magnetization. Furthermore, the results of in vitro experiments indicated that iron oxide-PEG-COOH nanoparticle is more cytotoxie than iron oxide-PAA nanoparticle due to different coordinating modes.