研究太赫兹时域光谱(TerahertzTime-domainSpectroscopy,THz-TDS)技术和红外光谱技术用于硫酸软骨素掺假鉴定的可行性.将六偏磷酸钠混入鲨鱼硫酸软骨素中的样品作为掺假研究对象,利用上述两种技术对样品进行对比研究.研究发现,THz光谱和红外光谱谱图中六偏磷酸钠标样、鲨鱼硫酸软骨素标样与掺假(混合)样品谱线均表现出较明显的差异,可用于鉴别鲨鱼硫酸软骨素的六偏磷酸钠掺假.实验结果表明,此两种技术能够鉴别的六偏磷酸钠:鲨鱼硫酸软骨素最低质量比分别为1:15和1:1,THz-TDS表现出较为灵敏的检测性能;综合考虑,THz-TDS技术可以比较好的用于鲨鱼硫酸软骨素的六偏磷酸钠掺假检测.本工作为发展一种基于THz-TDS技术的准确、快速和无损鉴别鲨鱼硫酸软骨素掺假的新型光谱技术奠定了前期实验基础.
A comparison of the feasibilities of adulteration detection for chondroitin sulfate using tera- hertz time-domain spectroscopy(THz-TDS)and infrared spectroscopy(IR) was conducted. The shark- derived chondroitin sulfate (SCS) mixed with sodium hexametaphosphate (SHMP) adulteration was used as the materials for detection in this research. The results have shown that the spectra of SHMP, SCS and the adulterated samples of them were significantly different in either THz-TDS spectra or IR spectra, indicating that these two spectroscopic techniques have a potential for the identification of chondroitin sulfate adulteration. The lowest adulteration ratios( mass to mass)of SHMP to SCS whichcan be identified were 1:15 and 1:1 for THz-TDS and IR, respectively. THz-TDS is more sensitive in the detection performance than IR and is superior to IR for the detection of SCS adulteration. This stud- y has provided an experimental foundation for developing an accurate, rapid and nondestructive spec- troscopic technique which can be used to identify the adulteration of SHMP in SCS.