在癌症房间的机械性质的变化的更好的理解能帮助为癌症的诊断,预防,和治疗提供新奇答案。我们因此基于在一台原子力量显微镜和目标的硅尖端之间的接触压力开发了细胞内部的有弹性的模量的一个计算模型房间,和切的深度。卵巢的房间(UACC-1598 ) 和结肠癌房间(NCI-H716 ) 用一个原子力量显微镜硅尖端被切成顺序的层。当 Ge 内容更慢慢地增加时,房间上的切的区域是 8 m。根据试验性的数据,在 Ge 内容(x) 和 F (GeH4 ) 之间的一种新关系 /F (SiH2Cl2 ) 质量流动比率被推出:x 2.5/(1x )= nF (GeH4 )/F (SiH2Cl2 ) 。SiGe 生长率和 Ge 内容与增加反应堆房间压力改善。由选择合适的先锋流动和反应堆压力,有一样的 Ge 的 SiGe 电影满足能在各种各样的温度被制作。然而, SiGe 晶体的质量清楚地依赖于免职温度。在更低的免职温度,更高水晶的质量被完成。因为生长率戏剧性地与更低的温度落下,最佳生长温度一定是在水晶的质量和生长率之间的妥协。X 光检查衍射,拉曼散布光谱学和原子?
Better understanding of variations in the mechanical properties of cancer cells could help to provide novel solutions for the diagnosis, prevention, and treatment of cancers. We therefore developed a calculation model of the intracellular elastic modulus based on the contact pressure between the silicon tip of an atomic force microscope and the target cells, and cutting depth. Ovarian cells (UACC-1598) and colon cancer cells (NCI-H716) were cut into sequential layers using an atomic force microscope silicon tip. The cutting area on the cells was 8 ~tm x 8 ~tm, and the loading force acting on the cells was increased from 17.523 to 32.126 μN. The elastic modulus distribution was measured after each cutting process. There were significant differences in contact pressure and cutting depth between different cells under the same loading force, which could be attributed to differences in their intrinsic structures and mechanical properties. The differences between the average elastic modulus and surface elastic modulus for UACC-1598 and NCI-H716 cells were 0.288±0.08 kPa and 0.376±0.16 kPa, respectively. These results demonstrate that this micro-cutting method can be used to measure intracellular mechanical properties, which could in turn provide a more accurate experimental basis for the development of novel methods for the diagnosis and treatment of various diseases.