蚌类蛋白质结构中起黏附作用的为多巴(DOPA)分子,其衍生物——聚多巴胺(PDA)常作为黑色素类似物被广泛应用于各领域。虽然目前PDA的形成机理仍很难被明确阐述,但这并不阻碍其在各个领域发挥强大的功效。由于PDA既具有强黏附性又富含各种官能团,其可在不同材质表面进一步反应形成功能层,从而实现对材料表面的功能化改性。鉴于科研工作者对PDA的浓厚兴趣,本文综述了其发现、形成机理的发展过程以及PDA功能化纳米粒子的研究,包括PDA功能化金属纳米材料、还原石墨烯材料、磁性纳米粒子和PDA纳米材料,展望了其发展前景。
Polydopamine (PDA), the derivative of 3, 4-dihydroxy-L-phenylalanine which plays the adhesive role in the mussel protein structure, as melanin analogues is widely used in various fields. Even though the mechanism for the polymerlization of PDA is still unclear, it has not prevented PDA from playing crucial roles in various fields. PDA has been given a gift that it can react to form a functional layer on the different material surface owing its strong adhesive and numerous functional groups. The surface of those materials, therefore, can be functionally modified by PDA. Driven by the interest in PDA, in this paper we reviewed the discovery of PDA, the mechanism for the formation of PDA, the PDA functional nanoparticles (including PDA functional metal nano-materials, PDA functional reduced graphene materials, PDA functional magnetic nanoparticles and PDA nanoparticles) and the development prospects of PDA.