瞄准:为文饰给证据为有不同淋巴的早胃的癌症的外科的治疗节点地位。方法:经历了胃切除术,超过 15 淋巴结检索了的一系列 322 个早胃的癌症病人在这研究被考察。淋巴节点转移的率是计算的。Univariate 并且多,变量分析被执行为预言淋巴评估独立因素节点转移。结果:没有转移在 No.5 被检测, 6 个淋巴节点(行) 在近似胃的癌症全胃切除术期间,并且在 No.10, 11p, 11d 在期间为脾和脾的动脉并且在 No.15 行的联合切除术在横向的结肠肠系膜的联合切除术期间。No.11p, 12a, 14v 行为转移被证明否定。全球 metastastic 率为行是 14.6% , 5.9% 为粘膜,并且 22.4% 为粘膜下层癌分别地。在组 II 的转移几乎在 No.7 被限制, 8a 行。Multivariate 分析鉴别侵略,组织学的类型和淋巴的侵略的深度是为行转移的独立风险因素。从远侧的癌症的没有转移(【= 在直径的 1.0 厘米) 在组 II 行被检测。当直径超过了 3.0 厘米时,转移率显著地增加了。所有肿瘤(【= 在直径的 1.0 厘米) 与转移和粘膜侵略显示出的行,一种沮丧的宏观的类型,和所有耸出的癌是 】 在直径的 3.0 厘米。结论:加 D1/D1 + No.7 的 Segmental/subtotal 胃切除术应该为癌被执行(【= 在直径,耸出的类型和粘膜侵略的 1.0 厘米) 。大部胃切除术正 D2 或 D2 + No.7, 8a,, 9 是最合理的操作 No.11p, 12a, 14v 淋巴腺切除术不应该习惯性地被推荐因为糟糕区分了并且压抑粘膜下层癌的类型(】 在直径的 3.0 厘米) 。全胃切除术不应该被执行在近似,那么确实联合切除术或 D2+/D3 淋巴腺切除术。
AIM: To give the evidence for rationalizing surgical therapy for early gastric cancer with different lymph node status. METHODS: A series of 322 early gastric cancer patients who underwent gastrectomy with more than 15 lymph nodes retrieved were reviewed in this study. The rate of lymph node metastasis was calculated. Univariate and multivariate analyses were performed to evaluate the independent factors for predicting lymph node metastasis. RESULTS: No metastasis was detected in No.5, 6 lymph nodes (LN) during proximal gastric cancer total gastrectomy, and in No.10, 11p, 11d during for combined resection of spleen and splenic artery and in No.15 LN during combined resection of transverse colon mesentery. No.11p, 12a, 14v LN were proved negative for metastasis. The global metastastic rate was 14.6% for LN, 5.9% for mucosa, and 22.4% for submucosa carcinoma, respectively. The metastasis in group Ⅱ?was almost limited in No.7, 8a LN. Multivariate analysis identified that the depth of invasion, histological type and lymphatic invasion were independent risk factors for LN metastasis. No metastasis from distal cancer (≤ 1.0 cm in diameter) was detected in group Ⅱ?LN. The metastasis rate increased significantly when the diameter exceeded 3.0 cm. All tumors (≤ 1.0 cm in diameter) with LN metastasis and mucosa invasion showed a depressed macroscopic type, and all protruded carcinomas were 〉 3.0 cm in diameter. CONCLUSION: Segmental/subtotal gastrectomy plus D1/D1 + No.7 should be performed for carcinoma (≤ 1.0 cm in diameter, protruded type and mucosa invasion).Subtotal gastrectomy plus D2 or D1 + No.7, 8a, 9 is the most rational operation, whereas No.11p, 12a, 14v lymphadenectomy should not be recommended routinely for poorly differentiated and depressed type of submucosa carcinoma (〉 3.0 cm in diameter). Total gastrectomy should not be performed in proximal, so does combined resection or D2^+/D3 lymphadenectomy.