中文摘要：

目的研究当孕妇面对可能发生的各类胎儿异常时对终止妊娠的态度。方法对前来广州医科大学附属第三医院产检的孕20~24周孕妇进行问卷调查,孕妇需要回答如果检查发现胎儿患致死性疾病,或生长发育受限,或存在明显功能障碍的结构异常,或仅有轻微甚至无功能障碍的结构异常时,是否选择终止妊娠。结果总计493名孕妇完成了问卷调查,其中493(100%)人表示将在发现胎儿存在致死性异常后终止妊娠,而在胎儿生长受限、有明显功能障碍的结构缺异常和无或有轻微功能障碍的结构缺异常等方面,分别有243(49.3%)、371(75.3%)和290(58.8%)人要求终止妊娠。影响孕妇决定是否终止妊娠的具有统计学意义的因素是本孕为珍贵儿(P【0.05)。结论多数孕妇在发现胎儿疾病后倾向于终止妊娠,即使胎儿疾病为非致死性的。

英文摘要：

Objective To study the attitudes of pregnant women towards the termination of pregnancy for fetal abnormality.Method Questionnaires were completed by all pregnant women attending routine ultrasound screening for malformation between 20~24 week of gestation.They were asked whether they would opt for termination of the pregnancy in case the fetus was diagnosed with one of the following abnormalities:lethal anomaly,anomaly causing developmental delay,structural abnormalities with severe physical dysfunction, structural abnormalities with mild physical dysfunction or without physical dysfunction.Logistic regression analysis was used to examine the effect of a variety of demographic and socio-economic characteristics in their choices.Results A total of 493 women completed the question-naires out of which 493 (100%)would terminate the pregnancy in case of lethal fetal anomaly.The corre-sponding figures for anomaly causing developmental delay,structural abnormalities with severe physical dysfunction,structural abnormalities with mild physical dysfunction or without physical dysfunction were 243(49.3%)、371(75 .3%)and 290(58.8%).A total of 313 (64.7%)would request late termination ow-ing to severe anomaly.The only one statistically significant factor would influence the maternal decision on pregnancy termination were precious baby (p < 0.05 ).Conclusions The majority of pregnant women would terminate pregnancy for fetal anomaly even though the abnormalities were non-lethal.