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分子干预治疗促进灵长类动物急性脑中风损伤后神经功能的重建及其机制探讨
  • 项目名称：分子干预治疗促进灵长类动物急性脑中风损伤后神经功能的重建及其机制探讨
  • 项目类别：国际(地区)合作与交流项目
  • 批准号：81020108021
  • 项目来源：国家自然科学基金
  • 研究期限：1900-01-01-1900-01-01
  • 项目负责人：高艳琴
  • 依托单位：复旦大学
  • 批准年度：2010
成果综合统计
成果类型
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  • 期刊论文
  • 会议论文
  • 专利
  • 获奖
  • 著作
  • 18
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期刊论文
Omega-3 Polyunsaturated Fatty acids in the Brain: Metabolism and Neuroprotection.
Focal cerebral ischemia activates neurovascular restorative dynamics in mouse brain
The dynamics of the mitochondrial organelle as a potential therapeutic target
Delivery of Neurotherapeutics across the blood brain barrier in stroke
Transgenic Overproduction of Omega-3 Polyunsaturated Fatty Acids Provides Neuroprotection and Enhanc
APE1 upregulation reduces oxidative DNA damage and protects hippocampal neurons from ischemic injury
Preconditioning Provides Neuroprotection in Models of CNS Disease Part I: Paradigms and Clinical sig
Phosphorylation of HSP27 by Protein Kinase D Is Essential for Mediating Neuroprotection against Isch
HSP27 protects the blood-brain barrier against ischemia-induced loss of integrity
Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning.
Scriptaid, a new histone deacetylase inhibitor, protects against traumatic brain injury via modlatio
miT-15b Suppression of Bcl-2 Contributes to Cerebral isschemic Injury and is Reversed by Sevflurane
Molecular dialogues between the ischemic brain and the peripheral immune system: Dualistic roles in
Drug-Induced Hypothermia in Stroke Models: Does it Always Protect?
Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white
会议论文
Regulatory T cell Transplantation Inhibits cerebral Endothelial Inflammation in Mice Transient Focal
Omega-3 Polyunsaturated Fatty Acid Supplementation Improves Neurological Recovery and Attenuates Whi
Food Restriction Attenuates ischemic neural Injuty and Facilitates Functional Recovery in Mice.
Bumetanide attenuates white Matter Injury and Protects the Blood Brain-Barrier in a Mouse Model of T
PTEN modulates white Matter Recovery after Traumatic Brain Injury.
Omega-3 Polyunsaturated Fatty Acids markedly attnauate Damage to white matter and the Blood-Barrain-
Anti-apoptotic mechanisms are involved in sevoflurane preconditioning against focal cerebral ischemi
免疫调控对脑卒中后神经血管单元的保护作用
Microglia/macrophage Polarization Dynamics Reveal Novel Mechanism of Injuyt Expansion after Focal Ce
N-3 Polyunsaturated Fatty Acids Protect Against Acute Cerebral Ischemia and Promote Revascularizatio
L-Serine Treatment Confers Neuroprotection Against Permanent Focal Cerebral ischemia in Rats via Imp
Scriptaid, a novel histone decetylase inhibitor protects against tramatic brain injury via modulatio
Prophylactic Supplementation of Omega-3 Polyunsaturated Fatty Acids Attenuates White Matter Injury a
Ethyl pyruvate treatment attenuates white matter injury and improves neurological recovery after tra
Edaravone Treatment Confers Neuroprotection Against Traumatic Brain Injury in Rats.
Sevoflurane preconditioning conferred neuroprotection via attenuating blood-brain-barrier damage aft
Temporal dynamics of endogenous neurogenesis, angiogenesis and oligodendrogenesis after focal cerebr
Omega-3 polyunsaturated fatty acids protect against ischemic neuronal death and neonatal hypoxic/isc
高艳琴的项目
缺血性脑中风中NAMPT通过小胶质细胞介导髓磷脂吞噬作用保护白质损伤的新颖机制研究
预防或治疗性给与Omega-3 PUFAs对老年鼠缺血损伤后长期神经功能重建的影响及其机制探讨
期刊论文 18 会议论文 17
纳米-HSP27药物对缺血性脑卒中的保护作用及其对BBB完整性保护的机制研究
PKCzeta-抑制肽对缺血性损伤的神经保护作用及其机制
期刊论文 4
HSP27在缺血性脑损伤神经元凋亡通路中的作用靶点及其神经保护作用
期刊论文 10
一种新型高效融合蛋白PTD-AIP对缺血性损伤海马神经元的保
期刊论文 5 会议论文 5