位置：立项数据库 > 立项详情页
云南有毒两栖动物肽类活性物质结构与功能及作用机制
  • 项目名称：云南有毒两栖动物肽类活性物质结构与功能及作用机制
  • 项目类别：联合基金项目
  • 批准号：U1132601
  • 项目来源：国家自然科学基金
  • 研究期限：1900-01-01-1900-01-01
  • 项目负责人：张云
  • 依托单位：中国科学院昆明动物研究所
  • 批准年度：2011
成果综合统计
成果类型
数量
  • 期刊论文
  • 会议论文
  • 专利
  • 获奖
  • 著作
  • 59
  • 0
  • 0
  • 4
  • 0
期刊论文
Venomics and Transcriptomic Analysis of Centipede Scolopendra subspinipes dehaani.
Adenosine-5'-triphosphate (ATP) protects mice against bacterial infection by activation of t
A novel antimicrobial peptide from skin secretions of the tree frog Theloderma kwangsiensis
A novel frog skin peptide containing function to induce muscle relaxation
Promoter hypermethylation and down-regulation of trefoil factor 2 in human gastric cancer
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica
Circulating serum trefoil factor 3 (TFF3) is dramatically increased in chronic kidney disease
Naturally occurring antimicrobial peptide OH-CATH30 protects against sepsis by regulating host innat
Peptidomics combined with cDNA library unravel the diversity of centipede venom
An immunoregulatory peptide from tsetsefly salivary glands ofGlossina morsitans morsitans
A novel ranacyclin-like peptide with anti-platelet activity identified from skin secretions of the f
Purification and characterization of cholecystokinin from the skin of salamander Tylototriton verruc
Host-derived, pore-forming toxin-like protein and tref
Novel analgesic peptides from the tree frog of Hyla japonica
Therapeutic potential of the antimicrobial peptide OH-
A small peptide with potential ability to promote wound healing.
Prohibitin is involved in the activated internalization and degradation of protease-activated recept
Host-derived, pore-forming toxin-like protein and trefoil factor complex protects the host against m
A potent anti-thrombosis peptide(vasotab TY) from horsefly salivary glands
Therapeutic Potential of the Antimicrobial Peptide OH-CATH30 for Antibiotic-Resistant Pseudomonas ae
Trefoil factor 1 gene alternations and expression in colorectal carcinomas
Vascular endothelial growth factor fromTrimeresurus jerdoniivenom specifically binds to VEGFR-2
Two new types of allergens from the cockroach, Periplaneta americana
Novel Peptides from Skins of Amphibians Showed Broad-Spectrum Antimicrobial Activities
A mycobacteriophage-derived trehalose-6,6=-dimycolatebinding peptide containing both antimycobacteri
YY-39, a tick anti-thrombosis peptide containing RGD domain
The Chemistry and Biological Activities of Peptides from Amphibian Skin Secretions
Small-anion selective transmembrane"holes" induced by an antimicrobial peptide too short t
Prohibitin is involved in the activated internalization and degradation of protease-activated recep
Drug target mining and analysis of the Chinese tree shrew for pharmacological testing
A potential wound-healing-promoting peptide from salamander skin
Aberrant Expression of Trefoil Factor 3 Is Associated With Colorectal Carcinoma Metastasis
A small peptide with therapeutic potential for inflammatory acne vulgaris
Molecular cloning and characterization of a complement-depleting factor from king cobra, Ophiophagus
A novel myotropic peptide from the skin secretions of the tree frog, Polypedates pingbianensis
A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1
Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel
Phenolic acids isolated from the fungus Schizophyllum commune exert analgesic activity by inhibiting voltage-gated sodium channels
Identification and characterization of a novel neuropeptide（neuropeptide Y-HS） from leech salivary gland of Haemadipsa sylvestris
Purification and characterization of cholecystokinin from the skin of salamander Tylototriton verrucosus
获奖
人前列腺液抗肿瘤及微生物多肽的分离纯化及活性研究
基于生物生存策略的有毒动物中药功能成分定向挖掘技术体系
人前列腺液抗肿瘤及微生物多肽的分离纯化及活性研究
基于生物生存策略的有毒动物中药功能成分定向挖掘技术体系
张云的项目
蛇毒专一性蛋白酶结构与功能及其对血液凝固系统的作用
期刊论文 9
两栖动物肽类毒素分子结构与功能多样性及环境适应机制
期刊论文 39 获奖 2
离子通道类疾病及天然药物研发研讨会
抑素蛋白(prohibitin)1调控蛋白酶激活受体(protease-activated receptor)1内化转运及降解的功能和机制
期刊论文 1
新型孔道形成蛋白和三叶因子复合物天然免疫功能和机制
两栖动物新型孔道形成毒素类似蛋白ALPs的生物学功能研究
大蹼铃蟾蛋白酶抑制分子克隆和肿瘤细胞凋亡机制研究
期刊论文 11 会议论文 1 著作 15
大蹼铃蟾皮肤三叶型蛋白结构与功能及其血小板活化机制
期刊论文 23 会议论文 2
非晶状体betagamma-晶状体蛋白与三叶因子复合物在大蹼铃蟾皮肤中的生物学功能和作用机制
期刊论文 17