中文摘要：

目的：目的：应用事件相关电位（ERP）P_（300）和MMN诊疗新技术,在本市和外省8家单位临床精神分裂症评估中进行推广。方法：方法：统一布置检查方法、统一技术参数和统一技术标准,对684例精神分裂症申请的P_（300）和MMN进行分析。结果：（1）3家单位初发精神分裂症P_（300）的异常检测率分别为48.0%、51.7%和53.3%,8家单位复发精神分裂症P_（300）的异常检测率分别为57.4%、52.4%、70.5%、63.2%、56.6%、64.3%、45.9%和59.0%。（2）3家单位初发精神分裂症MMN的异常检测率分别为48.0%、51.7%和53.3%,8家单位复发精神分裂症MMN的异常检测率分别为57.4%、52.4%、70.5%、63.2%、56.6%、64.3%、45.9%和59.0%。结论：ERP中的P_（300）、MMN新技术较适合精神科临床,提升了上海市精神卫生服务水平。

英文摘要：

Objective ：To generalize the new diagnosis technology application of event-related potential（ERP） P_（300） and MMN in the assessment of schizophrenia in 8 medical institutions. Methods：Analyzing the 684 patients′P_（300） and MMN with unified inspection method, technical parameter and technical standard. Results：（1） Abnormal detection rate of P_（300） in first-episode schizophrenia in 3 institutions was respectively 48.0%, 51.7% and 53.3%. Abnormal detection rate of P_（300） in relapse of schizophrenia in four institutions was respectively 57.4%, 52.4%, 70.5%, 63.2%, 56.6%, 64.3%, 45.9% and 59.0%.（2） Abnormal detection rate of MMN in first-episode schizophrenia in three institutions was respectively 48.0%, 51.7% and 53.3%. Abnormal detection rate of MMN in relapse of schizophrenia in three institutions was respectively 57.4%, 52.4%, 70.5%, 63.2%, 56.6%, 64.3%, 45.9% and 59.0%. Conclusion：The new technology of P_（300） and MMN in ERP is suitable for psychiatric clinical and enhance the level of mental health services in Shanghai.