中文摘要：

NP， P， M， F， HN 和副粘病毒天津紧张的 L 蛋白质的氨基酸序列被使用生物信息学方法分析。种系发生的分析基于在天津紧张和 25 paramyxoviruses 之中的 6 结构蛋白证明天津紧张属于类 Respirovirus，在亚科 Paramyxovirinae，并且是最仔细与仙台病毒(SeV ) 有关。有 14 已知的 SeVs 的种系发生的分析证明那个天津种类代表了一个新进化的系。类似比较显示那天津种类 P 蛋白质糟糕被保存，当 L 蛋白质是保存的大多数时，分享有已知的 SeVs 的 78.7%91.9% 仅仅氨基酸身份，有 96.0% 有已知的 SeVs 的 98.0% 氨基酸身份。6 结构蛋白的氨基酸序列的排列清楚地证明那个天津种类在他们的蛋白质序列拥有了许多唯一的氨基酸替换， 15 在 NP， 29 在 P， 6 在 M， 13 在 F， 18 在 HN，并且 29 在 L。这些结果表明那个天津种类是最可能的 SeV 的新遗传型。唯一的氨基酸替换的存在建议那个天津种类也许在 biological 有重要差别，病理学，从已知的 SeVs 的免疫学的，或流行病学的特征。

英文摘要：

The amino acid sequences of the NP, P, M, F, HN and L proteins of the paramyxovirus Tianjin strain were analyzed by using the bioinformatics methods. Phylogenetic analysis based on 6 structural proteins among the Tianjin strain and 25 paramyxoviruses showed that the Tianjin strain belonged to the genus Respirovirus, in the subfamily Paramyxovirinae, and was most closely related to Sendai virus （SeV）. Phylogenetic analysis with 14 known SeVs showed that Tianjin strain represented a new evolutionary lineage. Similarities comparisons indicated that Tianjin strain P protein was poorly conserved, sharing only 78.7% - 91.9% amino acid identity with the known SeVs, while the L protein was the most conserved, having 96.0% - 98.0% amino acid identity with the known SeVs. Alignments of amino acid sequences of 6 structural proteins clearly showed that Tianjin strain possessed many unique amino acid substitutions in their protein sequences, 15 in NP, 29 in P, 6 in M, 13 in F, 18 in HN, and 29 in L. These results revealed that Tianjin strain was most likely a new genotype of SeV. The presence of unique amino acid substitutions suggests that Tianjin strain maybe has a significant difference in biological, pathological, immunological, or epidemiological characteristics from the known SeVs.