中文摘要：

副粘病毒天津紧张，仙台病毒的新遗传型，从在狨殖民地死于严重呼吸感染的普通棉花耳朵狨的肺被孤立。在有尖锐的呼吸的道感染的小孩子的 19.28% IgM 积极的率建议了在天津紧张和人之间的一种靠近的关系。Hemagglutinin-neuraminidase (HN ) 是它为病毒的附件，穿入和版本负责的主要 transmembrane glycoprotein。为了清除在 HN 结构和副粘病毒天津紧张， rHN1，重叠的 rHN2 和 rHN3 的功能之间的关系， HN 蛋白质的 ectodomain 被表示。他们到对列性感冒病毒的标准反时代的抗原性和 hemaglutination 活动，以及生气反应打 A，类型 B 被分析。显示的结果表示了 rHNs 有自然抗原性。片断 rHN2 比在片断 rHN3 和 rHN1 发现拥有在本国的 HN 蛋白质的表面上暴露的更线性的 epitopes。片断 rHN3 的红血球凝聚活动比高片断 rHN2 和 rHN1，并且部分依赖于 HN3 的三维的符合构造蛋白质。在对列性感冒病毒类型 A 的 rHNs 和标准反时代之间跨反应，类型 B 建议 rHNs 可能不作为特定的抗原是最好的选择在临床的浆液标本检测病毒。

英文摘要：

Paramyxovirus Tianjin strain, a new genotype of Sendai virus, was isolated from the lungs of common cotton-eared marmoset that died of severe respiratory infection in the marmoset colonies. The 19.28% IgM positive rate in the young children with acute respiratory tract infection suggested a close relationship between Tianjin strain and humans. Hemagglutinin-neuraminidase （HN） is its major transmembrane glycoprotein responsible for viral attachment, penetration and release. To clear the relationship between HN structure and function of paramyxovirus Tianjin strain, rHN1, rHN2 and rHN3 overlapping the ectodomain of HN protein were expressed. Their antigenicity and hemaglutination activity, as well as cross reactivity to standard antisera against influenza virus type A, type B were analyzed. The results indicated expressed rHNs have the natural antigenicity The segment rHN2 possesses more linear epitopes exposed on the surface of the native HN protein than found in segments rHN3 and rHN1. The hemagglutination activity of segment rHN3 is higher than that of segments rHN2 and rHN1, and partially dependent on the three-dimensional conformation of HN3 protein. Cross-reactivity between rHNs and standard antisera against influenza virus type A, type B suggested that rHNs might not be the best alternative as specific antigens to detect virus in clinical serum specimens,