中文摘要：

ObjectiveTo 检验 Aspidopterys obcordata 的一篇水的摘录的尖锐毒性(一。obcordata ) 在 Sprague Dawley rats.MethodsThe，老鼠是口头上地管理了 5000 mg/kg 身体重量的剂量并且为 6 h 然后日报连续地观察了 14 天。控制老鼠被管理提取了水。一般行为，身体重量，和食物和水吸入上的摘录的效果被测量。在 14 天以后，老鼠被牺牲，他们的机关(肝，心，怒气，肺，肾，肾上腺，卵巢，和睾丸) 为宏观的检查被移开。除了血液学的身体和机关重量(例如，血红素和白血房间数) 并且临床的血生物化学(例如，白朊和 bilirubin ) 也是 examined.ResultsThere 记录的死亡，和老鼠都没与 A 被对待。obcordata 没显示出毒性的迹象。在与 A 对待的老鼠的所有测量参数。当时， obcordata 是未受影响的与那些相比在控制老鼠。尖锐毒性(LD50 ) 被估计是 > 5000 mg/kg 身体 weight.ConclusionOur 结果表明 A 的一篇水的摘录的一个尖锐口头的政府的安全。在老鼠的 obcordata 并且显示稍尖的那未来和 A 测试的长期的毒性。obcordata 被保证。

英文摘要：

OBJECTIVE： To examine the acute toxicity of an aqueous extract of Aspidopterys obcordata（A. obcordata） in Sprague Dawley rats.METHODS： The rats were orally administered a dose of 5000 mg/kg body weight and observed continuously for 6 h and then daily for 14 days. Control rats were administered distilled water. The effect of the extract on general behavior, body weight, and food and water intake were measured.After 14 days, the rats were sacrificed and their organs（liver, heart, spleen, lungs, kidney, adrenal glands, ovaries, and testes） were removed for macroscopic examination. The body and organ weights in addition to hematology（e.g., hemoglobin and white blood cell counts） and clinical blood biochemistry（e.g., albumin and bilirubin） were also examined.RESULTS： There were no deaths recorded, and the rats treated with A. obcordata showed no signs of toxicity. All measured parameters in rats treated with A. obcordata were unaffected when compared with those in control rats. The acute toxicity（LD_（50））was estimated to be 5000 mg/kg body weight.CONCLUSION： Our results demonstrate the safety of an acute oral administration of an aqueous extract of A. obcordata in rats and indicate that future subacute and long-term toxicity testing of A. obcordata is warranted.