中文摘要：

二氧化钛纳米颗粒（Ti O2-NPs）在广泛使用的同时也带来了潜在的环境污染、生态和健康风险。随着Ti O2-NPs的废弃量逐年上升,其与环境中重金属的联合毒性特别是对生态环境的影响逐渐引起国内外研究者重视。结合近几年国内外对二者相互作用的研究,重点综述Ti O2-NPs与铅（Pb）、镉（Cd）和砷（As）之间的联合毒性,并对存在的问题和今后的关注重点进行探讨。

英文摘要：

Although titanium dioxide nanoparticles （TiO2-NPs） have been widely used for years, they may potentially cause environmental pollution and ecological ＆ health risks at the same time. With the increasing release of TiO2-NPs, the combined toxicity of TiO2-NPs and heavy metals have become an important issue and caused great research interests. This review focused on the eombined toxicity of TiO2-NPs and heavy metals including lead, cadmium and arsenic, the existing problems, and the prospective in the field.