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中文摘要：
骨肉瘤是人类最常见的原发性恶性骨肿瘤，多发于青少年，其恶性程度很高，常常危及生命。利用动物模型对该病进行研究，是进一步探索其病因和治疗方法的重要手段之一。自发肿瘤模型，诱发肿瘤模型和移植肿瘤模型是日前通常被采用的骨肉瘤动物模型建立方法。本文对骨肉瘤动物模型的分类，建立办法及其应用方法进行综述。
英文摘要：
Osteosarcomas are the prominent primary bone cancers in human. They mainly affect children and adolescents and are usually highly aggressive and eventually lethal. The laboratory aninal model is one of the most important methods for studying the cause and therapeutic strategies of human osteosarcoma. Spontaneous model, chemical induced model and transplanted model are the usual methods of establishing animal model with this malignant tumor. This review summarized the classification of the animal model, methods of its establishment and its current applications in the research for osteosarcoma.
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