中文摘要：

目的应用计算流体力学软件对颅内长形动脉瘤进行三维数值模拟，以分析其血液动力学特性。方法对象为10例长形动脉瘤，其中8例曾经有蛛网膜下腔出血史。联合应用Matlab软件、Ansys软件、Fluent软件及自写程序对其进行计算机数值模拟。结果长形动脉瘤模型流人道的血流速度[（1．07±0．23）m／s]、动压[（574±186）Pa]及壁面切应力[（7．7±2．0）Pa]最高，流出道次之，顶部血流速度[（0．15±0．07）m／s]、动压[（37±13）Pa]及壁面切应力[（0．40±0．13）Pa]最低；瘤内不形成或仅形成简单涡流。结论长形动脉瘤顶部是动脉瘤破裂的主要部位，可能与动脉瘤顶部血流速度、动压及壁面切应力均最低有关。搏动性血流对动脉瘤的发生、生长和破裂起有重要作用。

英文摘要：

Objective To establish a model of three-dimensional numerical simulation of intracranial longitypical aneurism and analyze the hemodynamic features thereof. Methods Ten patients with intracranial longitypical aneurism underwent surgical treatment. Intracranial vascular uhrasonography was conducted before operation. Intra-operatively three-dimensional angiography of the aneurysm was conducted and multifunctional physiological monitor was used to record the dynamic pressure and pressure wave form of the main branch parent artery. Matlab, Ansys, and Fluent softwares were used to simulate the blood flow of the longitypical aneurisms. Results The hemodynamic parameter levels were the highest at the inflow tract, followed by those at the outflow tract, and were the lowest at the top of aneurysm, for example, the blood flow velocity was （1.07 ± 0.23 ） m/s, the dynamic pressure was （574 ± 186 ） Pa, and the wall shear stress was （7.7 ±2.0） Pa at the inflow tract, all significantly higher than those at the top [ （0.15 ± 0.07 ） m/s, （ 37 ± 13 ） Pa, and （0.40 ± 0.13 ） Pa respectively, all P 〈 0.05 ]. No eddy or just simple eddy occurred in the aneurysm. Conclusion The dynamic pressure, velocity, and wall shear stress are the lowest at the top of longitypical aneurysm which may contribute to the rupture of aneurysm.