为经常发生在年轻 adults.Surgery 的0.1%主要大脑肿瘤的背景中央 neurocytoma 帐号是为中央 neurocytoma 和直到学习试图估计 transcortical 的效果的超过90% .This 的5年的幸存活动范围的率的主要治疗情感和认知功能上的中央 neurocytoma 的外科的切除术的正面的途径在 surgery.Methods 电话后面起来访问以后的 5 年在这 study.By 被使用测试的 neuropsychological 的工具, assayed 情感,存储器
Background Central neurocytoma accounts for 0.1% of primary brain tumor that often occurs in young adults. Surgery is the main treatment for central neurocytoma and the rate of 5-year survival reaches up to over 90%. This study aimed to assess the effect of transcortical frontal approach to surgical resection of central neurocytoma on emotion and cognitive function 5 years after surgery. Methods Telephone following-up visits were used in this study. By means of neuropsychological testing, assayed emotion, memory and abstract thinking ability of 18 patients undergoing central neurocytoma resection by transcortical frontal approach for 5 years or more, with another 21 normal cases as control group were enrolled. The data were analyzed statisticaJly by paired t test with SPSS11.5. Results Patients whose central neurocytoma was removed by transcortical frontal approach were not affected on calculating ability 5 years after operation while ability of memory declined sharply (P=-0.000), the older, the more sharply (P=0.036). Ability of abstract thinking was significantly reduced (P=0.000), the older, the more significantly as well (P=-0.012); additionally, anxiety and depression occurred in patients rather more than those of control group (P=0.000), especially cognitive impairment. Conclusions Transcortical frontal approach for surgical resection of central neurocytoma has certain long-term influence on patients' life quality, vulnerable to anxiety, depression and cognitive impairment, the severity of which was correlated to age. Therefore, imDrovina suroical aoDroach will be of value for better Iona-term life aualitv of oatients.