中文摘要：

以硫酸盐为原料，氢氧化钠为沉淀剂制备了不同化学组成的纳米级锰锌铁氧体，采用X射线衍射分析（XRD）、透射电镜（TEM）及热重分析系统对其进行表征；并探讨了在20℃室温，200kHz的交变磁场下锰锌铁氧体磁流体热效应情况。实验结果表明：制备的锰锌铁氧体为尖晶石结构，圆形，平均粒径在50nm左右，粒度较均匀，居里温度随Zn^2＋含量的增加而降低；其在交变磁场作用下具有明显的热效应，升温可至肿瘤热疗的有效温度范围；且升温的速度及恒定时的温度与锰锌铁氧体的含量、磁场强度有关，含量高，场强大，升温速度快，恒定温度高；另外，在其它条件相同时，恒定时所能达到的温度随Zn^2＋含量的增加而降低。本研究为肿瘤热疗的控温、恒温奠定了基础。

英文摘要：

With the sulfate as the materials and NaOH as precipitator, Mn-Zn ferrite nanoparticles composed of different chemical components were prepared and characterizated by X-ray diffraction（XRD） ,transmission electron microscopy （TEM） and the heat analysis system. Besides, the heat effect was studied under given room temperature 20℃ and 200kHz alternating magnetic field in vitro. The results show that the prepared MnxZn1-xFe2O4 nanoparticles were spinel Mn-Zn ferrite, global, average diameter of 50nm. The curie temperature of MnxZn1-xFe2O4 decreased with the increase of Zn^2＋ . The MnxZn1-xFe2O4 nanoparticles had very distinct heat effect in a alternating magnetic field, and the speed of heating and the steady temperature increased with the increased of magnetic strength and the concentration of MnxZn1-xFe2O4 nanoparticles;decreased with the increased of Zn^2＋ . They can rise to a steady temperature for tumor hyperthermia. The study gives a way for solving the problem of controlling and stabilizing temperature at tumor hyperthermia.