目的总结我院膀胱黏膜修复尿道下裂的经验。方法回顾性总结我院1997年2月~2006年12月采用膀胱黏膜尿道成形术治疗的尿道下裂患者70例,年龄1—33岁,平均(14±9)岁,术后随访3个月~1年,平均(5±1)月。阴茎外观满意,排尿功能良好。将资料按手术年份、尿道下裂类型、患者年龄、手术分期等分组,对术后并发尿瘘情况应用SPSS15.0统计学软件进行统计学分析。结果术后并发尿瘘5例(7.1%),于术后3—6个月行尿瘘修补术后治愈;尿道狭窄2例(2.9%),经术后尿道扩张治愈。各组尿瘘发生率:前期手术组与近期手术组、前段型和中段型组与后段型组差异,有统计学意义(P〈0.05)。初次手术组与再次手术组、青春期前组与青春期后组之间差异无统计学意义(P〉0.05)。结论膀胱黏膜尿道成形术是较为理想的尿道下裂手术方式,膀胱黏膜更适合于后段型尿道下裂患者,患者年龄与手术分期对膀胱黏膜尿道成形术术后并发尿瘘无明显影响。
Objective To submit the experience of hypospadias repair using the bladder mucosa graft urethroplasty (BMG procedure) in our hospital. Methods From February 1997 to December 2006, seventy patients with hypospadias were underwent the BMG procedure and the clinical data were analyzed retrospectively. The mean age was (14±9)years (1 to 33 years). The mean (SD) period of follow up was (5± 1) months. According to the operation time, the patients' age and the different type of hypospadias, these cases were divided into several groups. Results Urethrocutaneous fistulas occurred in 5 patients (7.1%) and was repaired within 3 to 6 months. Urethral stenosis occurred in 2 patients (2.9%). There was statistically significant difference in the incidence of fistula between the previous operational group and the recent operational group, and so was between the posterior group and the anterior and middle group (P〈0.05). The opposite result was received between the pre-pubertal group and the pubertal and adult group and neither was between the primary operational group and the re-operational group (P〉 0.05). All patients were followed up more than three month. The neo-meatus was in the normal position. The results of penile cosmetic and urethral function were satisfactory. Conclusion Excellent neo-urethral functional and superior cosmetic results with low rate of complications can be gained by using bladder mucosa graft urethroplasty for the cases of hypospadias. The BMG procedure was more suitable to severe cases of the posterior hypospadias. The age of the patients and times of operation didn't contribute much to the operational complications.