目的通过Meta分析评价应用股方肌骨瓣移位联合空心螺钉固定术与单纯空心螺钉固定术治疗国人青壮年股骨颈骨折的疗效差异。方法利用CNKI中国期刊全文数据库及CBM光盘数据库、万方数据库,并辅以文献追溯、手工检索相关文献,收集2005年1月至2014年12月国内正式刊物上公开发表的有关应用股方肌骨瓣移位联合空心螺钉固定术与单纯空心螺钉固定术治疗股骨颈骨折病例对照研究的中文文献,严格评价纳入研究的文献质量及提取相关资料,运用RevMan5.0软件统计分析所有相关数据。结果共纳入8项研究。资料分析显示,与单纯应用空心螺钉固定治疗相比,股方肌骨瓣移位加空心螺钉固定治疗组骨折端愈合率较高[OR= 5.43,95%CI(2.89,10.20),P 〈 0.05],术后关节功能优良率较高[OR= 5.12,95%CI(3.21,8.17),P 〈 0.05],股骨头后期坏死率较低[OR= 4.21,95%CI(2.02,8.76),P 〈 0.05],骨折端愈合时间较短[WMD=-46.85,95%CI(-65.13,-28.56),P 〈 0.05]。结论对于国人青壮年股骨颈骨折,应用股方肌骨瓣移位联合空心螺钉固定术与单纯空心螺钉固定术相比,骨折端愈合率较高、术后髋关节功能较好、骨折端愈合时间较短,股骨头后期坏死率较低。
Objective To compare the efficacy of quadratus femoris muscle pedicle bone flap transplantation combined with hollow compression screw fixation versus hollow compression screw fixation in the repair of femoral neck fracture for young and middle-aged patients. Methods Case-controll studies comaring the quadratus femoris muscle pedicle bone flap transplantation with hollow compression screw fixation in the repair of femoral neck fracture were retrieved from CNKI, Chinese Biomedical Database, Wanfang Data and manually (from January, 2005 to December, 2014). Methodological quality of the trials was critically assessed, and relevant data were extracted. Statidtical software Revman 5.0 was used for data-analysis. Results Eight articles were included in the meta-analysis. The results showed that, compared the efficacy of quadratus femoris muscle pedicle bone flap transplantation combined with hollow compression screw fixation with hollow compression screw fixation,there were statidtical significance in the rate of fracture healing [OR = 5.43, 95%CI(2.89, 10.20), P 〈 0.05], the rate of good function of hip joint [OR = 5.12, 95% CI(3.21, 8.17), P 〈 0.05], the rate of femoral head necrosis [OR = 4.21,95%CI(2.02,8.76), P 〈 0.05], the time of fracture healing [WMD = -46.85, 95%CI(-65.13, -28.56), P 〈 0.05]. Conclusion The transplantation of quadratus femoris muscle pedicle bone flap combined with hollow compression screw fixation is superior to the hollow compression screw fixation in the repair of femoral neck fracture for young and middle-aged patients in regards to the rate of fracture healing, the rate of good function of hip joint, the rate of femoral head necrosis, the time of fracture healing.