目的探讨应用双极与单极人工股骨头置换术治疗老年移位型股骨颈骨折临床疗效的差异。方法利用Cochrane数据库、PUBMED数据库、CNKI中国期刊全文数据库及中国生物医学文献数据库、万方数据库,并辅以手工检索、文献追溯相关文献,收集1995年1月至2015年8月国内外正式刊物上公开发表的、有关应用单极与双极人工股骨头置换术治疗老年移位型股骨颈骨折对照研究的中英文文献,严格评价纳入研究的文献质量及提取相关资料,运用RevMan5.0软件统计分析所有相关数据。对数据进行异质性检验,用Meta分析方法对数据进行处理,评估其相对危险度(RR)值和95%可信区间(凹)。结果共纳入12项病例对照研究,共2368例患者。资料分析显示对于老年移位型股骨颈骨折,应用双极头置换治疗和应用单极头置换治疗股骨颈骨折,无论在术后患者死亡率[PaY=0.84,95%CI(0.50,1.43),P〉0.05]、总体并发症发生几率[RR=1.02,95%CI(0.77,1.36),P〉0.05]、术后关节脱位率[RR=0.60,95%CI(0.26,1.37),P〉0.05]、深部组织感染率[RR=1.60,95%CI(0.80,3.20),P〉0.05]、髋臼磨损率[RR=0.63,95%CI(0.39,1.03),P〉0.05]、再次手术率[RR=1.21,95%CI(0.62,2.35),P〉0.05]、患髋术后功能评分(Harris评分)[SMD:0.41,95%CI(-0.06,0.88),P〉0.05]等方面差异均无统计学意义。结论应用单极与双极人工股骨头置换术治疗老年移位型股骨颈骨折,两种方式均能得到基本满意的临床效果,两治疗组在术后患者死亡率、总体并发症发生率、关节脱位率、深部组织感染率、髋臼磨损程度、再手术率、患髋术后Harris评分等方面均无明显差异。但双极人工股骨头费用较高,临床医师应根据患者病情和经济情况进行选择。
Objective To compare the efficacy of using bipolar hemiarthroplasty with unipolar hemiarthroplasty in the treatment of displaced femoral neck fractures in the elder patients. Methods The studies using randomized controlled trials to compare the bipolar hemiarthroplasty with unipolar hemiarthroplasty in the treatment of displaced femoral neck fractures in the elder patients were retrieved from the Cochrane Library, Pubmed Data, CNKI, Chinese Biomedical Database, Wanfang Data and manually ( from January of 1995 to August of 2015 ). Methodological quality of the trials was critically assessed, and relevant data were extracted. Statistical software Revman 5.0 was used for data-analysis and the data was dealt by meta-analysis. The RR value and 95% CI were calculated. Results A total of 12 studies involving 2368 patients were included. The results showed that, comparing the efficacy of bipolar hemiarthroplasty with unipolar hemiarthroplasty in the treatment of displaced femoral neek fractures in the elder patients, no statidtieal signifieance was found in the rate of mortality [ RR = 0. 84, 95% CI( O. 50, 1.43), P 〉0.05], the overall complication [RR = 1.02, 95% CI(0.77,1.36), P 〉0.05], the dislocation rate [ RR = 0. 60, 95 % CI( 0. 26,1.37 ), P 〉 0. 05 ], the deep infection rate [ RR = 1.60, 95 % CI(0. 80,3.20), P 〉 0. 05 ], the aeetabulum erosion rate [ RR = 0. 63, 95% CI(O. 39,1.03 ), P 〉 0. 05 ], the reoperation rate [ RR = 1.21, 95 % CI(0. 62,2. 35 ), P 〉 0. 05 ], or the comparison of Harris hip HHS score [SMD =0.41, 95% CI( - 0.06,0.88), P 〉0.051. Conclusions Both bipolar and unipolar hemiarthroplasty for the treatment of the elderly patients suffering displaced femoral neck fracture achieved similar and satisfy clinical effect in the period of follow-up time. Unipolar hemiarthroplasty seems to be a more cost-effectiveness option for the elderly patients. According to specific conditions and request of the patients, the two methods should he selected respectively.