中文摘要：

目的探讨长期食用何首乌后,小鼠造血系统的变化。方法小鼠随机分为2组,对照组,喂饲正常饲料;何首乌饲料组,喂饲添加何首乌的饲料,10个月后,处死小鼠,应用流式细胞仪分析外周血、脾脏、胸腺及骨髓中各种细胞。结果何首乌饲料组小鼠,脾脏B细胞增多,胸腺CD4＋细胞增多,CD8＋细胞减少;骨髓造血干细胞显著减少,其中静止期细胞增多,增殖分裂期细胞减少。结论长期适量食用何首乌有助于减缓小鼠造血系统的衰老,维持造血系统稳定。

英文摘要：

Objective To investigate the effects of long-term consumption of Fallopia multiflora on mouse hematopoietic system. Methods Forty 10-month old female C57BL/6J mice were equally divided into two groups at random, the control group fed with normal food, and the experimental group, given food with added Fallopia multiflora. After 10 month, the mice were sacrificed, and the peripheral blood, spleen, thymus and bone marrow ceils were examined by flow cytometry. Results In the mice fed with Fallopia multiflora, the percentage of B cells in the spleen and CD4 ~ cells in the thymus were increased, and CD8~ cells in the thymus and bone marrow hematopoietic stem cells were decreased, among the bone marrow cells, GO cells were increased, but G1 and G2/S/M cells decreased. Conclusions Long-term proper consumption of Fallopia multiflora can delay the ageing of the hematopoietic system, and sustain its stability.