中文摘要：

针对醋酸与异丁烯加成酯化可逆反应温度低、精馏分离温度高的特点,采用带侧反应器的反应精馏集成过程（SRC）建立了低温反应与高温精馏集成的醋酸叔丁酯生产新工艺。固定塔釜上升汽化量100 kmol·h^-1,规定新鲜醋酸进料的转化率达到99.9%、醋酸叔丁酯选择性达到97.0%,采用过程模拟考察了进入侧反应器的精馏塔采出量、精馏段塔板数、侧反应器进出口间隔塔板数和侧反应器台数等参数对合成醋酸叔丁酯的SRC过程的影响。模拟结果表明,醋酸与异丁烯加成酯化生产醋酸叔丁酯的SRC过程中只有反应能力与分离能力达到最佳匹配才能使单位产品的生产成本最小。研究结果为醋酸叔丁酯生产新工艺的放大设计与优化奠定了基础。

英文摘要：

An advanced technology integrating a high-temperature distillation column with low-temperature side reactors（SRC） was proposed fortert-butyl acetate productionvia the additive esterification of acetic acid and isobutylene, since the reaction and separation required completely different operations. With a vapor boilup rate of 100 kmol·h^-1, acetic acid conversion of 99.9% andtert-butyl acetate selectivity of 97.0%, the effects of flow rate from distillation column to reactors, stage number of rectification zone, side-reactor number and interval stage number between inlet and outlet of the reactor were systemically investigated. The results demonstrated that a higher economy process could be achieved with a more optimized match between the reaction capability and the separation capability. The obtained results laid a foundation for design and optimization of the industrial SRC process.