目的:观察大株红景天注射液联合波立维治疗急性脑梗死的临床疗效。方法:将135例患有急性脑梗死的病人随机分为两组:对照组,67例,在常规治疗基础上给予波立维75 mg口服,1/d,共30 d;治疗组,68例,在常规治疗基础上给予大株红景天注射液10 mL静滴,1/d,同时给予波立维75 mg口服,1/d,共30 d。治疗后观察并比较患者的病死率、血液流变学、神经功能缺损情况、临床疗效以及不良反应等方面的差异。结果:两组在病死率方面的比较不具有统计学差异(P〉0.05);治疗组在提高临床疗效、降低神经功能缺损方面均优于对照组,具有统计学差异(P〈0.05);两组血液流变学指标组内比较具有统计学差异(P〈0.05),组间比较不具有统计学差异(P〉0.05);两组治疗过程中均未发生不良反应。结论:大株红景天注射液联合波立维治疗急性脑梗死可以降低神经功能损伤,在一定程度上提高了急性脑梗死的临床疗效。
Objective: To observe the differences between pure Polivy and Rhadiola extract injection combined with Polivy for the acute cerebral infarction patients' therapeutic effect.Methods: 135 cases cerebral infarction patients were randomly divided into Polivy group and Rhadiola extract injection combined with Polivy group.Based on the conventional treatment,Polivy group was treated with Polivy 75 mg by mouth once a day for 30 days.At the same time,the other group was treated with Rhadiola extract injection 10 ml by intravenous infusion once a day and Polivy for 30 days.All patients were observed and differences in the fatality,the therapeutic effect score,the neurological deficit score and the adverse effects were analyzed.Results: Rhadiola extract injection combination with Polivy is superior to pure Polivy in the improvement of therapeutic effect score and decrease of neurological deficit score(P0.05).After treatment,hemorheology indicators are better than before treatment in two groups(P0.05).However,the combined scheme is not bett-er than pure Polivy in the improvement of fatality(P0.05).Conclusion: Rhadiola extract injection combination with Polivy could improve the therapeutic effect and decrease the neurological deficit of the acute cerebral infarction patients.