中文摘要：

目的：探讨重组促黄体生成素在卵巢储备正常患者超促排卵中的作用及临床结局。方法：选择体外受精/胞浆内单精子注射-胚胎移植术（IVF/ICSI-ET）的患者200例,均有正常的卵巢储备,且均采用低剂量长效达菲林黄体期长方案。当主导卵泡大于13 mm时,随机分为三组,A组（加用乐芮）100例,B组（加用HMG）50例,C组50例（仅用FSH）。结果：①HCG日血清LH值：A组为（1.48±0.12）mIU/ml,B组（1.15±0.34）mIU/ml,C组为（0.5±0.9）mIU/ml,C组显著低于A组、B组,差异有统计学意义（P〈0.01）,A组与B组比较,差异无统计学意义（P〉0.05）。②HCG日E2值：A组（2 260.9±133.9）pg/ml和B组（2 065.8±176.2）pg/ml,显著高于C组（1 794.4±108.4）pg/ml,差异有统计学意义（P〈0.01）,A组与B组比较,差异无统计学意义（P〉0.05）。③HCG日E2值/≥14 mm卵泡数,A组（251.5±68.9）pg/ml明显高于B组（205.7±51.5）pg/ml。④获卵数、成熟卵子数、优质胚胎数及临床妊娠率A组、B组明显高于C组（P〈0.01）,优质胚胎数、临床妊娠率、种植率A组高于B组。结论：对于卵巢储备功能正常的不孕患者行黄体长方案促排中使用重组促黄体生成素能获得更好的临床结局。

英文摘要：

Objective To explore the clinical results of using rLH for controlled ovarian stimulation in patients with normal ovarian reserve undergoing IVF - ET. Methods We prospectively enrolled 200 patients with normal ovarian reserve who underwent IVF/ICSI - ET treatment and randomized them into three groups when the dominant follicle diameter 〉 13 mm. Group A （ n = 100） ： Patients were injected rLH in conjunction with rFSH. Group B （n = 50） ： Patients received HMG and rFSH. Group C （n = 50） ： Patients received only rFSH. Resuits In group C,serum levels of LH and E2 on the day of HCG administration were significantly lower than those in group A and B （P 〈 0. 01 ）. The numbers of ooeyte revealed, MII oocytes , superior quality embryos and pregnancy rate were significantly more in group A than those in the other two groups （ P 〈 0. 05 ）. Conclusion Using rLH for controlled ovarian stimulation in patients with normal ovarian reserve undergoing IVF - ET has better clinical outcomes comparing with no using it.