目的探讨脑干胶质瘤的临床特征及预后影响因素。方法完善脑干胶质瘤数据库,回顾性分析北京天坛医院2007年12月至2009年6月门诊及病房收治的134例脑干胶质瘤病人临床特征,分类汇总资料,分析影响生存期的因素。结果本组病人平均年龄为22.8岁,桥脑胶质瘤71例,占脑干胶质瘤53.0%,本组病人中位生存时间为10.79个月,儿童脑干胶质瘤,位于中脑桥脑的,弥散型的,未接受治疗的病人生存期短、预后差。结论脑干胶质瘤病人预后差,综合治疗能延长病人生存期。
Objective To determine the clinical characteristics of brainstem glioma and the prognosis factors. Methods Data of 134 patients in Beijing Tiantan Hospital neurosurgical inpatient and outpatient departments from Dec 2007 to June 2009 were evaluated by brainstem glioma databases. Results Meanages were 22.8, and pon gliomas were 71 cases (53.0%). Median survival time was 10. 79 months. The prognosis of brainstem glioma in children, pon lesion, infiltrated tumor and the untreated patients was poor than others. Conclusions Prognosis of brainstem glioma is poor. Multimodality treatment is helpful for these patients.