中文摘要：

采用玉米-豆粕型日粮研究铜（源于硫酸铜）对肉鸡肝细胞线粒体呼吸功能的影响。在对照组（Cu 11mg／k）基础上设3个高铜组（110mg／kg、220mg／k和330mg／kg，分别对应为：试验组Ⅰ、Ⅱ、Ⅲ），试验60d，在不同时间点（12、24、36、48、60日龄）采集肝脏提取线粒体。随着饲养时间的延长，对照组和试验Ⅰ组肝脏线粒体呼吸功能有增强的趋势。在48日龄之前，试验Ⅱ和Ⅲ组肝脏线粒体呼吸功能也有增强的趋势，但幅度较小，48日龄以后，肝脏线粒体呼吸功能呈现下降趋势，特别是60日龄的试验Ⅲ组。高铜日粮能影响肉鸡肝细胞线粒体的呼吸功能，日粮铜浓度为110mg／kg时，能增强线粒体的呼吸功能，但较高的铜浓度日粮则损害线粒体的呼吸功能。

英文摘要：

The effect of high-level copper （from copper sulfate） diet on mitochondrial respiratory function of liver in broiler was studied in this paper. Based on the control group （Cu 11 mg/kg）,three experimental groups were 110 mg/kg （group Ⅰ ）, 220 mg/kg （group Ⅱ ） and 330 mg/kg （group Ⅲ ） respectively,all of the experimental broilers were fed with corn-soybean meal containing copper from copper sulfate of different concentration concerned for 60 days,the mitochondrial respiratory function of liver in broiler were assayed at 12,24,36,48 and 60 days age. The results showed that,liver mitochondrial respiratory function experienced a enhanced trend with feed time,especially in group Ⅰ and Ⅱ. Liver mitochondrial respiratory function of group Ⅱ and Ⅲ still had enhanced trend before 48 days age,but the trend slowed down. Liver mitochondrial respiratory function show downward trend after 48 days age,especially group Ⅲ at 60 days age. High-level copper diet could affect the mitochondrial respiratory function of liver in broiler. When copper concentration in diet was 110 mg/kg,mitochondrial respiratory function could be enhanced,but the higher concentration of copper diet could damage mitochondrial respiratory function.