中文摘要：

心房颤动是临床最常见的慢性持续性心律失常,具有进行性、自我延续性的特点。MicroRNAs是新发现的基因表达调控因子,由长约22个核苷酸的单链RNA分子构成。MicroRNAs在控制房颤方面的潜在作用最近才开始研究,这些研究结果有助于了解房颤的分子机制。此综述简要叙述microRNAs的特点和功能、房颤的重构机制以及它们之间的关系。

英文摘要：

Atrial fibrillation（AF） is the most commonly encountered chronic sustained clinical arrhythmia,with a progressive,self-continuity features.microRNAs（miRNAs） are non-coding single-stranded RNAs with around 22 nucleotides in length.They play key roles in regulation of gene expression.The potential roles of miRNAs in controlling AF have recently been investigated.These findings help us better understand of the molecular mechanisms of AF.This article focuses on the characteristics of miRNAs and the mechanisms of atrial remodeling,recent progress in correlation between miRNA and atrial remodeling.