中文摘要：

近年来研究发现Wnt5a与肿瘤发生、发展关系密切。根据细胞类型不同，Wnt5a既可以起到促癌作用，又可以起到抑癌作用，其信号级联反应复杂，受多种因子调节。

英文摘要：

Recent studies suggest that Wnt5a is closely correlated with tumor genesis and progression. According to different cell types, Wnt5a may be a tumor stimulator or suppressor. WntSa signaling cascades are complex and intricate, and modulated by multiple regulatory factors.