中文摘要：

serotonin-transporter-linked 多态的区域(5-HTTLPR ) 与心情混乱被联系。这个协会被认为由于到由于减少的正面的外皮的控制的否定感情的刺激的杏仁之类 hyperresponsiveness。在白种人，短形式与这效果被联系，但是用汉汉语，我们最近发现长形式被包含。血清素受体在模式网络(DMN ) 区域和最近的研究发现了在 5-HTTLPR 和 DMN 的短形式之间的一个协会的缺省有富有的表示在白种人的功能的连接(FC ) 。现在的学习调查了是否在那里可以也是在对 DMN 的 5-HTTLPR 的这影响的种族差别。我们招募了 233 个年轻的汉中国对象并且计算了休息状态缺省网络 FC。我们的学习发现 L 搬运人减少了在在与 SS 相比的左 precuneus (Pcu ) 的双边的中间的前额的外皮，正确 parahippocampal 回转，左中间的时间的回转，和增加的 FC 的 FC。在 L 搬运人的 PCC-Pcu FC 否定地显著地与消沉分数被相关。我们的调查结果因此，建议也在在 5-HTTLPR 和 DMN 的不同形式之间的协会的白种人和汉汉语题目之间有差别功能的连接。

英文摘要：

The serotonin-transporter-linked polymorphic region （5-HTTLPR） is associated with mood disorders. This association is thought to be due to amygdala hyper- responsiveness to negative emotional stimuli as a result of reduced frontal cortical control. In Caucasians, the short form is associated with this effect, but in Han Chinese we recently found that the long form is involved. Serotonin receptors have rich expression in default mode network （DMN） regions and the recent studies have found an association between the short form of the 5-HTTLPR and DMN functional connectivity （FC） in Caucasians. The present study has investigated whether there may also be an ethnic difference in this influence of 5-HTTLPR on the DMN. We recruited 233 young Han Chinese subjects and calculated the resting-state default-network FC. Our study found that the L carriers had decreased FC in the bilateral medial prefrontal cortex, right parahippocampal gyrus, left middle temporal gyrus, and increased FC in left precuneus （Pcu） compared to SS. The PCC-Pcu FC in L carriers was significantly negatively correlated with the depression scores. Our findings, therefore, suggest that there is also a difference between Caucasian and Han Chinese subjects in the association between the different forms of the 5-HTTLPR and DMN functional connectivity.