中文摘要：

树枝状的房间(DC ) 被知道到目前为止是最强大的职业介绍抗原的房间。它能激活主要有免疫力的反应，并且另外 downregulate 免疫者反应。DC 有 immunoregulation 的一个独特人物。DC 签名，指定为 CD209 的一个分子，是 C 类型 lectin 总科的一个成员。它是模式识别受体，但是在 DC 的 immunoregulation 含有不仅。因为它的重要角色， DC 签名在调停成为了最近的研究的热点 DC 粘附，移植，发炎，激活的主要 T 房间，触发有免疫力的反应并且参予病原体和肿瘤的有免疫力的逃跑。涉及主要、第二等的有免疫力的反应和相关机制的 DC 签名上的这些研究将当然在治疗并且阻止某些疾病向我们提供一个新方法。细胞与分子的免疫学。2006； 3 (4 ): 279-283。

英文摘要：

Dendritic cells （DCs） are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. These studies on DC-SIGN involved in primary and secondary immune response and relevant mechanism will certainly provide us with a new method in treating and preventing certain diseases.