中文摘要：

N-烷基双哌啶与Boc保护的L-氨基酸反应,再经三氟乙酸脱Boc保护合成了两个新型手性双哌啶-α-氨基酰胺——3-[（2＇S,4＇R）-4＇-乙酰氧基-2＇-吡咯烷基]甲酰基-7-正丙基-3,7-二氮杂双环[3.3.1]壬烷和3-[（2＇S）-2＇-吡咯烷基）甲酰基-7-异丙基-3,7-二氮杂双环[3.3.1]壬烷,其结构经NMR,IR和MS表征。

英文摘要：

Two novel chiral bispidine-α-amino-amides,3-[（2′S）-2′-pyrrolidinyl]formoxyl-7-isopropyl-3,7-diazabicycolnonane and 3-[（2′S,4′R）-4′-acetoxy-2′-pyrrolidinyl]formoxyl-7-n-propyl-3,7-diazabicycolnonane were synthesized by the reaction of N-alkylbispidines with L-Boc-amino acids,then deprotect in the presence of trifloroacetic acid.The structures were characterized by NMR,IR and MS.