中文摘要：

GATA蛋白是一类重要的转录调节因子,它们具有保守的DNA结合结构域,其中的GATA 4、 5和 6亚家族对组织特异性基因的表达起关键性的调控作用.综述了这3种因子的结构功能,在小鼠中的表达模式和基因定位,在组织特异性基因表达中的作用,对可诱导基因表达的调节以及与它们相互作用的有关因子等.

英文摘要：

GATA proteins are important transcription factors,each of which contains a conserved DNA binding domain. As a subfamily of them, GATA4, 5, and 6 play critical roles in regulating tissuespecific gene expression. The structural function,expression patterns and gene targeting in the mouse,role in tissuespecific gene expression,regulation in inducible gene expression as well as the factors that interact with them are discussed.