将Boc-L-Pro-L-DOPA-OMe吸附在硅胶上,利用微波技术固相合成了cis-和trans-3-(3,4-二羟基苄基)。六氢吡咯并[1,2-α]哌嗪-1,4-二酮,合计收率70.2%,其结构经。HNMR,^13CNMR和HR-MS表征。
C/s- and trans-3-(3,4-dihydroxybenzyl) -hexahydropyrrolo [ 1,2-α ] piperazine-1,4-dione with yields of 70.2% were synthesized from Boc-L-Pro-L-DOPA-OMe absorbed on the silica gel under microwave irradiation by solid phase. The structures were identified by^ 1H NMR, ^13C NMR and HR- MS.