中文摘要：

包含偶氮苯(N-PNA ) 的肽 nucleic covalently 在薄片表面上被绑。互补 DNA 探针在薄片表面上用 pNa 由金 nanoparticles hybridizated 标记。杂交被显微镜学 mothed 成功地与 AFM 检测。位置的影响和偶氮苯在杂交上联合起来的 cis-trans 异构化与 AFM 被调查。

英文摘要：

Peptide nucleic acid containing azobenzene （N-PNA） was covalently bound on chip surfaces. Complementary DNA probes labeled by gold nanoparticles hybridizated with PNA on chip surfaces, The hybridization was successfully detected with AFM by the microscopy mothed. The influences of the position and the cis-trans isomerization of azobenzene unit on hybridization were investigated with AFM.